We have a long history of studying disease prevention and health promotion initiatives. Our staff has assessed programs to prevent childhood obesity and evaluated efforts that have shown promise in slowing the spread of the childhood obesity epidemic. We have identified interventions that promote better nutrition and increased physical activity, and examined efforts to reduce risky behaviors as a means of promoting public health. Our work in evaluating prevention models and interventions in the areas of smoking and substance abuse has produced valuable information to inform public health efforts. In addition, we are assessing pregnancy prevention models and evaluating programs promoting healthy pregnancies and maternal and child health.